Fibrodysplasia Ossificans Progressiva | ACVR1(c.617G>A; R206H) = Klassisk FOP

Artikel om potentiell medicin för FOP

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En artikel på Engelska i NCATS National Center for Advansing Translational Sience här kan du läsa hela artikeln.

Bone Morphongenetic Protein Inhibitors to Treat Fibrodysplasia Ossificans Progressiva
”Recently, the principal investigators identified the first small molecule inhibitor of BMP signaling. The compound, dorsomorphin, blocks BMP signaling by inhibiting BMP type I receptors…”

The resources and expertise of the TRND program are sought to complete: scaled-up synthesis; development of an optimal oral formulation; pharmacokinetic, ADME, and toxicology studies; product development planning and preparation for IND submission; and possibly, Phase I tolerability studies.”

”Framtiden är inte vad den brukade vara” ~ Yogi Berra

Marie H Fahlberg
Vinnare av IFOPAs Jennie Peeper Outstanding International Leadership Award 2012.
Nominerad till David Legas stipendium 2012.

Stöd FOP-drabbade genom bidrag till FOP-forskningen

Bankgiro 5823-7140.
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